# 1. A 65 lb. patient with acetaminophen toxicity needs a 5% solution of Acetylcysteine at 140 mg/kg loading dose, then 70 mg/kg q6h for 7 treatments.

January 6, 2020
###### CH03: The Human Body: Are We Really What We Eat? Focus Figure 3.12: Small Intestine Structure and Function ileocecal valve
January 6, 2020

1. A 65 lb. patient with acetaminophen toxicity needs a 5% solution of Acetylcysteine at 140 mg/kg loading dose, then 70 mg/kg q6h for 7 treatments. Acetylcysteine comes in a 20% solution and should be diluted with saline a. What is the loading dose (mg) for this patient? b. What is the total volume of fluid and medication that you will give to the patient for the loading dose? . Acetylcysteine i. Saline: c. What is the dose (mg) for the remaining treatments? d. What is the total volume of fluid and medication that you will give to the patient for the remaining doses? i. Acetyleysteine: i. Saline 2. A 35 lb. patient needs a rapid infusion of amphotericin B (100mg/20ml) for a fungal infection. The dose is 0.25mg/kg in 30 ml of D5W for a single treatment and then 0.5 mg/kg as prepared initially 3 times a week unti 12 mg/kg accumulated dosage is given. a. What is the initial dose (mg)? b. How many milliliters of medication is needed for the initial dose? c. For the initial dose, using 50% dextrose stock solution: . How many milliliters of water is needed? i. How many milliliters of dextrose is needed? d. What is the dose (mg) for the remaining treatments? e. How many milliliters of medication is needed for the remaining treatments? f. For the remaining treatments, using 50% dextrose stock solution: . How many milliliters of water is needed? i. How many milliliters of dextrose is needed? g. How many total treatments will be needed to reach the accumulated dosage? 3. A 82 lb patient needs 7 ml/kg of 7% hypertonic saline at a rate of <Iml/kg/min. The hypertonic saline at your practice is a 23% solution a. What is the dose (ml)? 0.25mg/kg in 30 ml of D5W for a single treatment and then 0.5 mg/kg as prepared initially 3 times a week until 12 mg/kg accumulated dosage is given a. What is the initial dose (mg)? b. How many milliliters of medication is needed for the initial dose? c. For the initial dose, using 50% dextrose stock solution: . How many milliliters of water is needed? i. How many milliliters of dextrose is needed? d. What is the dose (mg) for the remaining treatments? e. How many milliliters of medication is needed for the remaining treatments? f. For the remaining treatments, using 50% dextrose stock solution: i. How many milliliters of water is needed? i. How many milliliters of dextrose is needed? g. How many total treatments will be needed to reach the accumulated dosage? 3. A 82 lb patient needs 7 ml/kg of 7% hypertonic saline at a rate of<Iml/kg/min. The hypertonic saline at your practice is a 23% solution a. What is the dose (ml)? b. How many milliliters are needed if diluting with physiologic saline . Physiologic saline: i. 23% hypertonic saline: c. What is the maximum rate for this patient: . ml/min i. ml/hr: 4. A 12.5 lb. patient needs fluids at 65 m/kg/day at metoclopramide (10mg/2ml) at 1.5 mg/kg/day in a 500 ml bag of fluids a. What is the rate of fluids: b. How many milligrams of metoclopramide is needed: c. How many milliliters of metoclopramide is needed: 5. A 46 lb. postoperative patient needs fluids at 75 ml/kg/day with Lidocaine (2%) at 30 ug/kg/min, ketamine (100 mg/ml) at 5 ug/kg/min, and morphine (10 mg/ml) at 2.5 ug/kg/min a. What is the rate of fluids per hour b. How many milliliters of medication to add to a 1 L bag: . Lidocaine ii. Ketamine i. Morphine: