Bobby, a 13-year-old male, was hospitalized following a perforated appendix that required surgery. Bobby has an open wound requiring dressing changes twice daily. He is currently on contact precautions for a methicillin resistant staphylococcus aureus (MRSA) infection. The estimated date of discharge is five-to-ten-days post-op and will include long-term antibiotics and wound care.


Surgical site infections (SSIs) are a significant concern for patients who undergo surgery, contributing to increased morbidity, mortality, and healthcare costs. Methicillin-resistant Staphylococcus aureus (MRSA) infections are particularly challenging due to their resistance to commonly used antibiotics. Patients with MRSA infections require specialized and rigorous infection control measures to prevent the spread of this pathogen. This case study focuses on Bobby, a 13-year-old male, who developed a perforated appendix requiring surgery, resulting in an open wound. Bobby’s condition necessitates contact precautions for MRSA infection, long-term antibiotic therapy, and wound care. This paper will discuss the evidence-based methods for managing MRSA infections, wound care, and antibiotic therapy in pediatric patients.

Managing MRSA Infection

MRSA is a strain of Staphylococcus aureus that has acquired resistance to beta-lactam antibiotics, including methicillin. It poses a significant challenge in healthcare settings due to its ability to colonize and infect patients, leading to increased morbidity and mortality. Contact precautions are essential to prevent the transmission of MRSA. This includes the use of gloves, gowns, and hand hygiene.

Strict adherence to hand hygiene protocols is crucial in preventing the spread of MRSA. Healthcare providers should use soap and water or an alcohol-based hand rub before and after patient contact. Hand hygiene should be performed for at least 20 seconds, ensuring all surfaces of the hands are covered. Hand hygiene should be emphasized to Bobby, his family, and healthcare providers to reduce the risk of spreading MRSA.

In addition to hand hygiene, proper wound care is essential in managing MRSA infections. The wound should be assessed for signs of infection, such as redness, warmth, swelling, and purulent drainage. Bobby’s wound should be cleaned with an antimicrobial solution, such as chlorhexidine or povidone-iodine, and dressed with sterile dressings. Dressing changes should be performed with sterile gloves, and equipment should be discarded appropriately.

Antibiotic Therapy

Long-term antibiotic therapy is necessary to treat MRSA infections effectively. The choice of antibiotics should be guided by the susceptibility profile of the organism. In many cases, MRSA isolates are susceptible to newer agents, such as linezolid, daptomycin, and vancomycin. Vancomycin is often considered the drug of choice for serious MRSA infections, and it can be administered intravenously.

Once Bobby’s condition improves, he may be transitioned to oral antibiotics. Trimethoprim-sulfamethoxazole (TMP-SMX) is a common option for oral treatment, as it has good oral bioavailability and excellent activity against MRSA. The duration of antibiotic therapy depends on the severity of the infection, the site of infection, and the clinical response to treatment. Generally, a minimum of two weeks of therapy is recommended for uncomplicated skin and soft tissue infections.

Preventing Surgical Site Infections

Preventing SSIs in surgical patients requires a multidimensional approach that includes preoperative, intraoperative, and postoperative measures. Preoperative measures include patient optimization, such as ensuring adequate nutrition, glycemic control, and smoking cessation. Bobby’s overall health should be assessed to ensure he is optimally prepared for surgery.

Intraoperatively, strict adherence to sterile techniques is critical in reducing the risk of SSIs. This includes proper hand hygiene, appropriate surgical site preparation, sterile draping, and the use of antimicrobial prophylaxis. An appropriate prophylactic antibiotic should be administered within one hour before surgery initiation, taking into consideration Bobby’s MRSA status.

Postoperatively, wound care is crucial in preventing SSIs. The wound should be inspected for signs of infection, and appropriate dressings should be applied. Pain management is also essential to ensure the patient can move and cough effectively, reducing the risk of atelectasis and subsequent pneumonia.


In conclusion, managing MRSA infections in pediatric patients like Bobby requires a comprehensive approach that includes strict adherence to infection control measures, appropriate wound care, and targeted antibiotic therapy. Hand hygiene, contact precautions, and wound care are crucial in preventing the transmission and progression of MRSA infections. Long-term antibiotic therapy should be guided by the organism’s susceptibility profile and may include intravenous and oral antibiotics. Additionally, preventive measures must be implemented throughout the surgical journey to reduce the risk of SSIs. By implementing evidence-based practices, healthcare providers can effectively manage MRSA infections and promote optimal patient outcomes. Thus, it is crucial to ensure Bobby receives the necessary care and attention to facilitate his recovery and prevent complications associated with MRSA infection.

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