In Melnyk & Fineout-Overholt (2019) textbook Box 23.1 on page 682, select one of the Fifteen Ethical Principles of the Universal Declaration on Bioethics and Human Rights. State the principle and describe the importance of the selected principle to ethical research. In addition, describe how a researcher would ensure that this principle would be protected for human subjects in a research study. Initial Post:

The ethical principle selected from the Universal Declaration on Bioethics and Human Rights is Principle 2: Human dignity and human rights. This principle emphasizes the intrinsic worth of each individual and their entitlement to certain fundamental rights. It serves as a guiding principle in ensuring the ethical conduct of research involving human subjects.

The importance of Principle 2 lies in its recognition of the inherent value and dignity of every human being. In the context of research, this principle ensures that individuals are treated with respect and their rights are protected throughout the study. It acknowledges that subjects should not be exploited or used as mere means to an end, but rather as autonomous individuals with the right to make informed decisions regarding their participation.

Respect for human dignity and human rights is crucial in ethical research for several reasons. Firstly, it upholds the principle of beneficence, which requires researchers to prioritize the well-being and welfare of the subjects. By recognizing the dignity and rights of participants, researchers are obligated to protect their physical, psychological, and social well-being, ensuring that they are not exposed to unnecessary harm or exploitation.

Secondly, this principle is closely linked to the concept of autonomy, as it supports subjects’ right to self-determination and informed consent. It highlights the importance of obtaining voluntary and informed consent from participants, promoting their ability to make decisions based on adequate information and without coercion. Respecting human dignity and rights allows individuals to exercise their autonomy in choosing whether or not to participate in research, and if so, to what extent.

Furthermore, Principle 2 serves as a safeguard against discrimination and unjust treatment of vulnerable populations. It underscores the importance of fairness and equality in research, ensuring that all individuals, regardless of their social, cultural, economic, or health-related characteristics, are treated with dignity and have their rights protected. This is particularly relevant when conducting research involving marginalized or vulnerable populations, where there is a heightened risk of exploitation and discrimination.

To ensure the protection of Principle 2 in a research study involving human subjects, it is essential for researchers to implement several measures. Firstly, researchers must obtain informed consent from potential participants. This involves providing clear and comprehensive information about the study, its purpose, procedures, potential risks, benefits, and safeguards in a language and format that the participants can comprehend. Participants should have the opportunity to ask questions and make an autonomous decision based on their understanding.

Additionally, researchers should take precautions to ensure the privacy and confidentiality of participants’ personal information. Data collected during the study should be de-identified and stored in a secure manner, with only authorized personnel having access to the information. Participants should be assured that their identity and personal information will be kept confidential, thereby respecting their right to privacy and protecting their dignity.

Another crucial aspect is the equitable inclusion of participants, ensuring that the research population is representative and diverse. Researchers should make efforts to avoid bias in participant selection and to include individuals from different backgrounds, ages, genders, and socioeconomic statuses. This helps to prevent discrimination and ensures that research findings are applicable and generalizable to a wider population.

Furthermore, regular monitoring and oversight of the study should be conducted to ensure compliance with ethical standards and the protection of participants’ rights. Research ethics committees or institutional review boards play a significant role in reviewing and approving research protocols, providing an independent assessment of the study’s ethical implications. They ensure that the research design, informed consent process, data collection methods, and participant protection measures adhere to ethical principles, including human dignity and human rights.

In conclusion, Principle 2 of the Universal Declaration on Bioethics and Human Rights, which emphasizes human dignity and human rights, is of paramount importance in ethical research involving human subjects. It ensures that individuals are treated with respect, their rights are protected, and their autonomy is upheld. By obtaining informed consent, ensuring privacy and confidentiality, promoting equitable inclusion, and establishing oversight mechanisms, researchers can uphold and protect this principle in their studies, thereby contributing to ethically conducted research.

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